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Igor pro 6.3 serial3/18/2023 The IBP-O monitor reported errors during 54% of the measurements. Results are reported as mean bias (95% confidence intervals). Three-way anova, linear regression and Bland-Altman analyses were used to evaluate the IBP-D data. Measurements were also obtained in awake, restrained birds. Indirect blood pressure measurements were compared to direct systolic arterial pressure (SAP) and mean arterial pressure (MAP) during normotension and induced states of hypotension and hypertension. Direct arterial pressure measurements were obtained from the contralateral superficial ulnar artery. Birds were anesthetized and IBP measurements were obtained by oscillometry (IBP-O) and Doppler (IBP-D) on the pectoral and pelvic limbs using three cuffs of different width based on limb circumference: cuff 1 (20-30% of circumference), cuff 2 (30-40%), and cuff 3 (40-50%). Six, sex unknown, adult red- tailed hawks. To compare Doppler and oscillometric methods of indirect arterial blood pressure (IBP) with direct arterial measurements in anesthetized and awake red- tailed hawks. Zehnder, Ashley M Hawkins, Michelle G Pascoe, Peter J Kass, Philip H Published on behalf of the American Heart Association, Inc., by Wiley.Įvaluation of indirect blood pressure monitoring in awake and anesthetized red- tailed hawks (Buteo jamaicensis): effects of cuff size, cuff placement, and monitoring equipment. The differences between the simultaneous recordings by the 2 techniques should be recognized by researchers. However, the measurements between the 2 techniques are similar when tail-cuff readings are compared with telemetry readings in the nondisturbed mice. This study reveals that the tail-cuff technique underestimates the core blood pressure changes that occur simultaneously during the restraint and measurement phases. The tail-cuff readings significantly underestimated those from simultaneous telemetry recordings however, "nonsimultaneous" telemetry, obtained in undisturbed mice, were similar to tail-cuff readings obtained in undisturbed mice on the same day. Restraint induced the largest and sustained increase in cardiovascular parameters and temperature. The results revealed significant increases in central blood pressure, heart rate, and core body temperature from baseline following handling interventions without significant difference among the different handling technique, habituation, or sex of the investigator. Direct comparison of measurements obtained by telemetry and tail-cuff were made in the same mouse. This included comparison of handling techniques, operator's sex, habituation, and influence of hypertension induced by angiotensin II. C57Bl/6J mice were implanted with radio-telemetry probes to investigate the effects of the steps of the tail-cuff technique on central blood pressure, heart rate, and temperature. However, tail-cuff requires handling and restraint during measurement, which may cause stress affecting blood pressure and undermining reliability of the results. Telemetry, the "gold-standard" technique, is invasive and expensive and therefore tail-cuff, a noninvasive alternative, is widely used. Reliable measurement of blood pressure in conscious mice is essential in cardiovascular research. Wilde, Elena Aubdool, Aisah A Thakore, Pratish Baldissera, Lineu Alawi, Khadija M Keeble, Julie Nandi, Manasi Brain, Susan D Tail-Cuff Technique and Its Influence on Central Blood Pressure in the Mouse.
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